The Delta variant is changing and adds new mutations. The consensus sequence according to Pango has 30 mutations now. Notice that there are multiple definitions of Delta. The W.H.O defines the Delta differently – as Pango B.1.617.2. Pango B.1.617.2 is not Delta, but the top node of multiple lineages, also included in the Delta (AY.1, AY.2, … AY.30, …). The consensus sequence of B.1.617.2 has fewer mutations.

The real world has Pango Delta. The current Delta sequence (See the Characteristic mutations of Delta), including all the characteristic mutations, is dominant in the US, UK, and worldwide.

>70% in the US

USA, snapshot 2021-10-17

>90% in the UK

>80% Worldwide

(the sampling is biased)

Characteristic mutations of Delta
GENEAMINO ACID
ORF1aA1306S
ORF1aP2046L
ORF1aP2287S
ORF1aV2930L
ORF1aT3255I
ORF1aT3646A
ORF1bP314L
ORF1bG662S
ORF1bP1000L
ORF1bA1918V
ST19R
SE156G
Sdel157/158
SL452R
ST478K
SD614G
SP681R
SD950N
ORF3aS26L
MI82T
ORF7aV82A
ORF7aT120I
ORF7bT40I
ORF8S84L
ORF8del119/120
ND63G
NR203M
NG215C
ND377Y

The content of this article reflects the situation on the publication date.

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October 17, 2021