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Delta-ORF1a

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Now and for the last couple of weeks, the prevalent coronavirus variant is not Delta, but its subvariants AY.3 and AY.4. They are distinguished from Delta (B.1.617.2) by a set of point mutations in ORF1a.

These mutations in ORF1a might be responsible for the increased rate of growth.

AY.3-AY.4 subvariants represented 25%-30% of sequenced samples since early July, and might be responsible for higher severity of the cases. Now they represent more than 60%.

Work in Progress

via Science Defies Politics

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September 2, 2021